Cç. Bento Rocha Cabral, 14 (Largo do Rato) 1250-047 Lisboa, Portugal


A mais antiga Instituição privada portuguesa dedicada à Investigação Científica

O Instituto edita as publicações:

– Travaux de Laboratoire de l’Institut Rocha Cabral

 – Actualidades Biológicas

As publicações resultantes dos trabalhos desenvolvidos pelos seus investigadores encontram-se listadas abaixo:

(última atualização dezembro de 2019)

Efeito da toma de citrulina, um precursor da arginina sobre as atividades de enzimas eritrocitárias em ratos. Inácio A, Aguiar A, Gil A, Bicho M, 2019. Boletim da Sociedade Portuguesa de Hemorreologia e Microcirculação. Vol 34, nº 1, 5-9

Effects of combined training with different intensities on vascular health in patients with type 2 diabetes: a 1‐year randomized controlled trial. Magalhães JP, Melo X, Correia IR, Ribeiro RT, Raposo J, Dores H, Bicho M, Sardinha LB. Cardiovasc Diabetol. 2019 Mar 18; 18 (1): 34.

Interaction between HFE and haptoglobin polymorphisms and its relation with plasma glutathione levels in obese children. Aguiar L, Marinho C, Martins R, Alho I, Ferreira J, Levy P, Faustino P, Bicho M, Inácio A. Cell Mol Biol (Noisy‐le‐grand). 2019 Feb 28; 65 (2) :69‐74.

Psychosocial and Neurocognitive Factors Associated with Hepatitis C ‐ Implications for Future Health and Wellbeing. Barreira DP, Marinho RT, Bicho M, Fialho R, Ouakinin SRS. Front Psychol. 2019 Jan 9; 9: 2666.

Hepatitis C Pretreatment Profile and Gender Differences: Cognition and Disease Severity Effects. Barreira DP, Marinho RT, Bicho M, Flores I, Fialho R, Ouakinin S.Front Psychol. 2019 Oct 15; 10:2317

Hypertension and longevity: role of genetic polymorphisms in renin‐angiotensin‐aldosterone system and endothelial nitric oxide synthase. Pereira da Silva A, Matos A, Aguiar L, Ramos‐ Marques N, Ribeiro R, Gil Â, Gorjão‐Clara J, Bicho M. Mol Cell Biochem. 2019 May; 455 (1‐2): 61‐71.

Effectiveness of high‐intensity interval training combined with resistance training versus continuous moderate‐intensity training combined with resistance training in patients with type 2 diabetes: A one‐year randomized controlled trial. Magalhães JP, Júdice PB, Ribeiro R, Andrade R, Raposo J, Dores H, Bicho M, Sardinha LB. Diabetes Obes Metab. 2019 Mar; 21 (3): 550‐559.

Genetic predisposition for essential hypertension, based on studies of genetic polymorphisms in modern global human populations: The perspective of evolutionary biology. Bicho M. Rev Port Cardiol. 2018 Jun; 37 (6): 509‐510.

Characterization of Portuguese Centenarian Eating Habits, Nutritional Biomarkers, and Cardiovascular Risk: A Case Control Study. da Silva AP, Valente A, Chaves C, Matos A, Gil A, Santos AC, Gorjão‐Clara JP, Bicho M. Oxid Med Cell Longev. 2018 Mar 13; 2018: 5296168.

Genital mycoplasmas and ureaplasmas in cervicovaginal self-collected samples of reproductive-age women: prevalence and risk factors. Silva J, Cerqueira F, Teixeira AL, Bicho MC, Campainha R, Amorim J, Medeiros R Int J STD AIDS. 2018 Sep 29, 10, 999-1006.

Total Knockdown of LMW‐PTP in MDA‐MB‐231 Cells Reduces Osteoclastogenesis. Sapinho G, Alho I, Bicho M, Coelho C. Anticancer Res. 2017 Dec; 37 (12): 6671‐6677. Mountain Cycling Ultramarathon Effects on Inflammatory and Hemoglobin Responses. Alonso I, Matos A, Ribeiro R, Gil Â, Cardoso C, Sardinha LB, Bicho M. Med Sci Sports Exerc. 2018 Feb; 50 (2): 353‐360.

The main autoimmune and nonautoimmune etiologies of endogenous hyperthyroidism do not seem to influence the increased prevalence of morphometric vertebral fractures and osteoporosis in Portuguese men. Barbosa AP, Mascarenhas MR, Bicho M, Janeiro J, Oliveira AG. Osteoporos Sarcopenia. 2017 Sep; 3(3): 149‐154.

Is there a genetic support for the Cloninger (type I/II) clinical classification of alcohol addiction? Pombo S, Ferreira J, Levy PQ, Bicho M. Psychiatry Res. 2017 Dec; 258: 621‐623.

Coordination between antioxidant defenses might be partially modulated by magnesium status. Monteiro CP, Matias CN, Bicho M, Santa‐Clara H, Laires MJ. Magnes Res. 2016 Apr 1; 29 (4): 161‐168.

Sickle cell anemia ‐ Nitric oxide related genetic modifiers of hematological and biochemical parameters. Aguiar L, Matos A, Gil Â, Afonso C, Almeida S, Braga L, Lavinha J, Kjollerstrom P, Faustino P, Bicho M, Inácio Â. Clin Hemorheol Microcirc. 2016; 64 (4): 957‐963.

Hormonal modulation of novelty processing in women: Enhanced under working memory load with high dehydroepiandrosterone‐sulfate‐to‐dehydroepiandrosterone ratios. do Vale S, Selinger L, Martins JM, Bicho M, do Carmo I, Escera C. Neurosci Lett. 2016 Nov 10; 634: 98‐103.

Sarcopenia and osteoporosis in portuguese centenarians. da Silva AP, Matos A, Ribeiro R, Gil Â, Valente A, Bicho M, Gorjão‐Clara J. Eur J Clin Nutr. 2017 Jan; 71 (1): 56‐63.

Mechanisms underlying the association between obesity and Hodgkin lymphoma. Matos A, Marinho‐Dias J, Ramalheira S, Oliveira MJ, Bicho M, Ribeiro R. Tumor Biol. 2016 Oct; 37 (10): 13005‐13016.

Low Molecular Weight Protein Tyrosine Phosphatase Slow Isoform Knockdown in MDA‐MB‐ 435 Cells Decreases RAW 264.7 Osteoclastic Differentiation. Alho I, Costa L, Bicho M, Coelho C. Anticancer Res. 2016 May; 36 (5): 2227‐32.

Body Composition Assessment and Nutritional Status Evaluation in Men and Women Portuguese Centenarians. Pereira da Silva A, Matos A, Valente A, Gil Â, Alonso I, Ribeiro R, Bicho M, Gorjão‐Clara J. J Nutr Health Aging. 2016 Mar;20(3):256‐66.

Epistatic Interaction of CYP1A1 and COMT Polymorphisms in Cervical Cancer. Matos A, Castelão C, Pereira da Silva A, Alho I, Bicho M, Medeiros R, Bicho MC. Oxid Med Cell Longev. 2016; 2016: 2769804.

Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone‐sulfate (DHEAS) and emotional processing ‐ A behavioral and electrophysiological approach. do Vale S, Selinger L, Martins JM, Bicho M, do Carmo I, Escera C. Horm Behav. 2015 Jul; 73: 94‐103.

Association of myeloperoxidase polymorphism (G463A) with cervix cancer. Castelão C, da Silva AP, Matos A, Inácio Â, Bicho M, Medeiros R, Bicho MC. Mol Cell Biochem. 2015 Jun; 404 (1‐2): 1‐4.

Prevalence of silent vertebral fractures detected by vertebral fracture assessment in young Portuguese men with hyperthyroidism. Barbosa AP, Rui Mascarenhas M, Silva CF, Távora I, Bicho M, do Carmo I, de Oliveira AG. Eur J Endocrinol. 2015 Feb; 172 (2): 189‐94.

The role of CYBA (p22phox) and catalase genetic polymorphisms and their possible epistatic interaction in cervical cancer. Castaldo SA, da Silva AP, Matos A, Inácio Â, Bicho M, Medeiros R, Alho I, Bicho MC. Tumor Biol. 2015 Feb; 36 (2): 909‐14.

The relationship between dehydroepiandrosterone (DHEA), working memory and distraction‐‐ a behavioral and electrophysiological approach. do Vale S, Selinger L, Martins JM, Gomes AC, Bicho M, do Carmo I, Escera C. PLoS One. 2014 Aug 8; 9 (8): e104869.

In women with previous pregnancy hypertension, levels of cardiovascular risk biomarkers may be modulated by haptoglobin polymorphism. Matos A, Pereira da Silva A, Clara Bicho M, Afonso C, Areias MJ, Rebelo I, Bicho M. Obstet Gynecol Int. 2014; 2014: 361727.

The role of 5‐HTTLPR polymorphism in alcohol craving experience. Pombo S, Ferreira J, Cardoso JM, Ismail F, Levy P, Bicho M. Psychiatry Res. 2014 Aug 15; 218 (1‐2): 174‐9.

Anticancer activity of structurally related ruthenium (II) cyclopentadienyl complexes. Côrte‐Real L, Mendes F, Coimbra J, Morais TS, Tomaz AI, Valente A, Garcia MH, Santos I, Bicho M, Marques F. J Biol Inorg Chem. 2014 Aug; 19 (6): 853‐67.